Measurement of red blood cell mechanics during morphological changes

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چکیده

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Measurement of red blood cell mechanics during morphological changes.

The human red blood cell (RBC) membrane, a fluid lipid bilayer tethered to an elastic 2D spectrin network, provides the principal control of the cell's morphology and mechanics. These properties, in turn, influence the ability of RBCs to transport oxygen in circulation. Current mechanical measurements of RBCs rely on external loads. Here we apply a noncontact optical interferometric technique t...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2010

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0909533107